In Vitro Biology

ChemPartner offers a broad spectrum of high quality services with fast turnaround time to support all stages of drug discovery programs.  These services are applied in the following areas:  target cloning, assay development, HTS, primary and secondary cell-based assay, selectivity panel, signal transduction, and biomarker discovery in animal models for oncology, metabolic syndromes, inflammation/immunology and CNS diseases.

In addition, specific services are offered in the areas of in vitro biology, cell biology/pharmacology, and bioanalytical assays for large molecule drug development.

In Vitro Biology

• Molecular cloning
• Protein expression and purification
• Assay development
• Compound profiling
• High throughput screening with automated robotic system
• Kinase selectivity profiling
• Nuclear receptor selectivity profiling
• GPCR selectivity profiling
• Ligand affinity assay

We offer biological services in various drugable targets with current capacity focused on GPCRs, kinases, nuclear receptors, proteases, protein-protein interaction, and other various enzyme-related targets.  Assay detection formats include UV-Vis, fluorescence, FP, HTRF, luminescence, intracellular Ca mobilization, mobility shift assay by Caliper, and radioactivity.